Grab a medium-sized mixing bowl. Add your dry ingredients: the self-rising cornmeal, all-purpose flour, salt, black pepper, and garlic powder. Give them a little whisk or stir to combine everything evenly.
Finely dice the sweet onion and coarsely chop your dill pickles. Make sure your pickles are drained well! Add the diced onion and chopped pickles right into the bowl with your dry ingredients. Give it a stir to coat the pickles and onion with the flour mixture.
In a separate small bowl or just make a well in the center of your dry ingredients, lightly whisk the large egg and then stir in the buttermilk until combined. Pour this wet mixture into the bowl with the dry ingredients and pickle/onion mixture.
Using a spoon or rubber spatula, gently mix everything together until the dry ingredients are moistened and everything is combined. Do not overmix; a few lumps are fine.
Heat the vegetable oil in a large skillet over medium heat. The oil should be hot enough to fry and crisp the fritters but not so hot that it burns them.
Once the oil is ready (test by dropping a tiny bit of batter – it should sizzle gently), carefully drop spoonfuls of the batter into the hot oil using a tablespoon or small cookie scoop. Do not overcrowd the pan; work in batches if necessary.
Let the fritters cook for about 2-3 minutes per side, until they are golden brown and crispy on the outside and cooked through. Use a slotted spoon to carefully flip them over.
Once golden, remove the fritters from the oil and place them on a plate lined with paper towels to drain off any excess oil.
Serve your Fried Pickle Fritters warm. They are best fresh out of the pan.